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Registros recuperados : 24 | |
5. | | CASTELLS, D. Integrated parasite management strategies to control GIP (strategic control including nutrition, pasture rotation, anthelmintics, introduction to genetic selection, etc.). In: Regional Training Course on Genetics of Parasite Resistance in Sheep and Goats: Sampling, Data Collection, Management and Analyses, FAO/IAEA (International Atomic Energy Agency), December 5-9, 2016, Uruguay. 18 p.Biblioteca(s): INIA Las Brujas. |
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9. | | CASTELLS, D.; MEDEROS, A.; LORENZELLI, E.; MACCHI, I. Diagnóstico de resistencia antihelmíntica de Haemonchus contortus a las ivermectinas en el Uruguay. SUL Producción Ovina, 2002, v. 15, p. 43-48 Este artículo fue publicado, también en: Castells Montes, D., coord. Resistencia genética del ovino y su aplicación en sistemas de control integrado de parásitos. Montevideo (Uruguay): FAO, 2003. p. 61-66.Biblioteca(s): INIA Tacuarembó. |
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12. | | Bottaro, C.; Zavala, F.; Rabuffetti, A.; Castells, D.; Elizondo, J.; Marchesi, E. Efecto de la fertilización mineral NP en la producción estacional de pasturas naturales en algunos tipos de suelos : 1er año ln: Congreso Nacional de Producción Animal, 1 : 1973 abr : Paysandu Madalena, F.E. ; Rucks, C. ; Azzarini, M. (coord). [Memorias]. Paysandu (Uruguay): Facultad de Agronomía, 1973. p1-21Biblioteca(s): INIA La Estanzuela. |
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13. | | GRASSO, A.; GOLDBERG, V.; IRIARTE, W.; GIMENO,D.; CASTELLS, D.; RINCON, G.; NAVAJAS, E.; CIAPPESONI, G. Nuevas herramientas moleculares para la selección en ovinos: ejemplo de caso resistencia a parásitos gastrointestinales ln: Jornada técnica, VI Jornada de agrobiotecnología. INIA Las Brujas, 20 de octubre de 2012 Conocimiento intensivo para el sector productivo: situación actual y perspectivas. Canelones (UY): INIA, 2012. 7-9 (Serie Actividades de Difusión; 698)Biblioteca(s): INIA Las Brujas. |
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14. | | ESCRIBANO, C.; SARAVIA, A.; COSTA, M.; CASTELLS, D.; CIAPPESONI, G.; RIET-CORREA, F.; FREIRE, T. Resistance to Haemonchus contortus in Corriedale sheep is associated to high parasite-specific IgA titer and a systemic Th2 immune response. Scientific Reports, 1 December 2019, Volume 9, Issue 1, Article number 19579. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-019-55447-6 Article history: Received: 21 June 2019 / Accepted: 27 November 2019 / Published: 20 December 2019.
Funding information:
We acknowledge the personnel from Uruguayan Wool Secretariat that assisted with animal studies. This project was...Biblioteca(s): INIA Las Brujas. |
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15. | | BIANCHI, G.; GARIBOTTO, G.; OLIVEIRA, G.; BENTANCUR, O.; CASARETTO, A.; CASTELLS, D.; PLATERO, M.; NIN, J.; MORROS, J. Cruzamientos terminales sobre ovejas Corriedale en el Uruguay, 1. Velocidad de crecimiento, grado de terminación y dimensiones del M. longissimus dorsi en corderos livianos y pesados. ITEA Producción Animal, 1999, v. 95A, no. 3, p. 234-247Biblioteca(s): INIA Tacuarembó. |
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16. | | RODRIGUEZ, A.; CABRERA, P.; CIAPPESONI, C.; MONTOSSI, F.; CASTELLS, D.; MARTINO, P.; BONINO, J.; DE BARBIERI, I.; GIORELLO, D. Early detection of an artificial Haemonchus contortus infection in sheep using three different faecal occult blood tests In: World Buiatrics Congress, 26., Chile. 14-18 de Noviembre. 2010. AbstractBiblioteca(s): INIA Tacuarembó. |
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17. | | FERREIRA, G.; DE BARBIERI, I.; CASTELLS, D.; NAVAJAS, E.; GIORELLO, D.; COSTA, J.T.C.; BANCHERO, G.; CIAPPESONI, G. Differences in growth between Corriedale sheep divergent lines for resistance to nematodes. In: Annual Meeting of the European Federation of Animal Science, 70., Ghent, Belgium, 26-30 August, 2019. Book of abstracts No. 25. p. 574Biblioteca(s): INIA Tacuarembó. |
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18. | | FERREIRA, G.; CIAPPESONI, G.; CASTELLS, D.; AMARILHO-SILVEIRA, F.; NAVAJAS, E.; GIORELLO, D.; BANCHERO, G.; DE BARBIERI, I. Feed conversion efficiency in sheep genetically selected for resistance to gastrointestinal nematodes Animal Production Science, 2021, vol. 61(8), pages 754-760. OPEN ACCESS. doi: https://doi.org/10.1071/AN20121 Article history: Submitted: 24 March 2020 Accepted: 12 February 2021 Published online: 10 March 2021.Biblioteca(s): INIA Tacuarembó. |
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19. | | FERREIRA, G.; CIAPPESONI, G.; CASTELLS, D.; BANCHERO, G.; AMARILHO, F.; NAVAJAS, E.; GIORELLO, D.; DE BARBIERI, I. La resiliencia y la eficiencia en conversión de alimento en la producción ovina. Revista INIA Uruguay, 2020, no. 60, p. 27-30. (Revista INIA; 60)Biblioteca(s): INIA La Estanzuela; INIA Las Brujas. |
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20. | | CASTELLS, M.; GIANNITTI, F.; CAFFARENA, D.; CASAUX, M.L.; SCHILD, C.; CASTELLS, D.; RIET-CORREA, F.; VICTORIA, M.; PAREÑO, V.; COLINA, R. Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries. Archives of Virology,2019 Nov, Vol. 164 (11), p. 2715-2724. DOI: https://10.1007/s00705-019-04384-w Article history:Received 26 June 2019/Accepted 30 July 2019/Published 27 August 2019.Biblioteca(s): INIA La Estanzuela. |
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Registros recuperados : 24 | |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
27/01/2020 |
Actualizado : |
27/01/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
ESCRIBANO, C.; SARAVIA, A.; COSTA, M.; CASTELLS, D.; CIAPPESONI, G.; RIET-CORREA, F.; FREIRE, T. |
Afiliación : |
CECILIA ESCRIBANO, Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MONIQUE COSTA, Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; DANIEL CASTELLS, Secretariado Uruguayo de Lana, Florida, Uruguay; CARLOS GABRIEL CIAPPESONI SCARONE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; TERESA FREIRE, Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay. |
Título : |
Resistance to Haemonchus contortus in Corriedale sheep is associated to high parasite-specific IgA titer and a systemic Th2 immune response. |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
Scientific Reports, 1 December 2019, Volume 9, Issue 1, Article number 19579. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-019-55447-6 |
ISSN : |
2045-2322 |
DOI : |
10.1038/s41598-019-55447-6 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 21 June 2019 / Accepted: 27 November 2019 / Published: 20 December 2019.
Funding information:
We acknowledge the personnel from Uruguayan Wool Secretariat that assisted with animal studies. This project was funded by INIA (Uruguay) and CSIC-VUSP (Uruguay). C.E. was funded by a scholarship by INIA. |
Contenido : |
ABSTRACT.
Gastrointestinal nematode infections, including Haemonchus contortus, are one of the main causes of economic losses to ovine farmers worldwide. In order to contribute to the control of nematode infections and avoid parasite spreading we generated divergent resistant and susceptible sheep breeds and evaluated the adaptive immunity of these animals developed upon experimental infection against H. contortus. The selection of resistant or susceptible animals from the Corriedale Breed has been based on Expected Progeny Differences for faecal egg counts per gram. Furthermore, animals from the resistant Corriedale line were inseminated with imported semen from Australian Rylington Merino rams. Thus, the objective of this work was to analyze the adaptive immune response in both susceptible and resistant obtained lambs. Our results indicate that there is a potent parasite-specific local and systemic immune response in resistant animals and that although susceptible lambs can produce high levels of IgA antibodies during the infection, their antibody response is delayed which, together with an impaired specific-Th2 response, does not contribute to initial parasite elimination. Our results shed light into the immune mechanisms that mediate resistance to H. contortus and could constitute important assets to sheep farmers, not only as a means to detect resistance, but also to enhance the efficiency of selection in stud flocks.
© 2019, The Author(s). |
Palabras claves : |
HAEMONCHUS; SHEEP. |
Asunto categoría : |
L01 Ganadería |
URL : |
https://www.nature.com/articles/s41598-019-55447-6.pdf
|
Marc : |
LEADER 02635naa a2200253 a 4500 001 1060699 005 2020-01-27 008 2019 bl uuuu u00u1 u #d 022 $a2045-2322 024 7 $a10.1038/s41598-019-55447-6$2DOI 100 1 $aESCRIBANO, C. 245 $aResistance to Haemonchus contortus in Corriedale sheep is associated to high parasite-specific IgA titer and a systemic Th2 immune response.$h[electronic resource] 260 $c2019 500 $aArticle history: Received: 21 June 2019 / Accepted: 27 November 2019 / Published: 20 December 2019. Funding information: We acknowledge the personnel from Uruguayan Wool Secretariat that assisted with animal studies. This project was funded by INIA (Uruguay) and CSIC-VUSP (Uruguay). C.E. was funded by a scholarship by INIA. 520 $aABSTRACT. Gastrointestinal nematode infections, including Haemonchus contortus, are one of the main causes of economic losses to ovine farmers worldwide. In order to contribute to the control of nematode infections and avoid parasite spreading we generated divergent resistant and susceptible sheep breeds and evaluated the adaptive immunity of these animals developed upon experimental infection against H. contortus. The selection of resistant or susceptible animals from the Corriedale Breed has been based on Expected Progeny Differences for faecal egg counts per gram. Furthermore, animals from the resistant Corriedale line were inseminated with imported semen from Australian Rylington Merino rams. Thus, the objective of this work was to analyze the adaptive immune response in both susceptible and resistant obtained lambs. Our results indicate that there is a potent parasite-specific local and systemic immune response in resistant animals and that although susceptible lambs can produce high levels of IgA antibodies during the infection, their antibody response is delayed which, together with an impaired specific-Th2 response, does not contribute to initial parasite elimination. Our results shed light into the immune mechanisms that mediate resistance to H. contortus and could constitute important assets to sheep farmers, not only as a means to detect resistance, but also to enhance the efficiency of selection in stud flocks. © 2019, The Author(s). 653 $aHAEMONCHUS 653 $aSHEEP 700 1 $aSARAVIA, A. 700 1 $aCOSTA, M. 700 1 $aCASTELLS, D. 700 1 $aCIAPPESONI, G. 700 1 $aRIET-CORREA, F. 700 1 $aFREIRE, T. 773 $tScientific Reports, 1 December 2019, Volume 9, Issue 1, Article number 19579. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-019-55447-6
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